Curriculum Vitae
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Raphael B. Stricker, M.D.
Personal Data  

Raphael B. Stricker, M.D.
Union Square Medical Associates
450 Sutter Street Suite 1504
San Francisco, CA 94108

Phone: (415) 399-1035
Fax: (415) 399-1057
Date of Birth: 1/7/50
Birthplace: New York, NY
Citizenship: USA
Marital Status: Married
Wife: Abigail A. Stricker
Children: Zoe Ruth Stricker, born 2/10/93
Avi David Stricker, born 6/2/94

 

Education  

1961-67                       Horace Mann High School, Bronx, NY.  Diploma 6/67.
1967-71                       Columbia College, New York, NY.  BA 6/71
1972-75                       University of Lausanne Medical School, Lausanne, Switzerland
1975-78                       Columbia University College of Physicians & Surgeons, New York, NY. MD 6/78

 

Postgraduate Training and Appointments

1978-81

Residency: Internal Medicine, St. Luke's-Roosevelt Hospital
Center, New York, NY
 
1981-84 Fellowship: Hematology/Oncology, Cancer Research Institute, University of California Medical Center, San Francisco, CA
 
1984-85 Postdoctoral Research Scholar, Cancer Research Institute, University of California Medical Center, San Francisco, CA
 
1985-86 Instructor in Medicine, Cancer Research Institute, UCSF Instructor, Department of Laboratory Medicine, UCSF
 
1986-89 Assistant Professor, Department of Laboratory Medicine UCSF
Assistant Professor, Department of Medicine, UCSF
 
1989-91 Associate Director, Division of Immunotherapy and Plasmapheresis Unit, Children's Hospital of San Francisco
 
1991-93 Associate Director, Division of Immunotherapy and Plasmapheresis Unit, California Pacific Medical Center, San Francisco
 
1993-95 Associate Medical Director, HemaCare Corporation, San Francisco, CA
 
1995-97 Associate Medical Director, The Barron Centers, San Francisco, CA
 
1997-Present Medical Director, Union Square Medical Associates, San Francisco, CA
   

Honors and Awards

1967                            Cum Laude Society, Horace Mann Chapter

1968-71                       Dean's List, Columbia College

1972-75                       Medical Honors, University of Lausanne Medical School

1975-78                       Honors in Medicine, Neurology, and Psychiatry,

                                  Columbia University College of Physicians and Surgeons

1982-84                       NIH Research Grant #HL-07100-08 454965-31779,

                                    Cancer Research Institute, University of California Medical

                                    Center, San Francisco, CA

1984-85                       Individual NRSA #1F32 HL-06871-01 CLN, National

                                    Heart, Lung and Blood Institute

1985-86                       Research Fellowship, 85-N27A, American Heart

                                    Association, California Affiliate

1986-87                       Research Fellowship, 86-N37A, American Heart

                                    Association, California Affiliate

1986-87                       Academic Senate Research Grant, University of

                                    California San Francisco

1986-89                       AIDS Clinical Research Grant, University of

                                    California San Francisco

1987-89                       NIH RO1 AI/HL 24288, National Heart, Lung and Blood

                                    Institute/National Institute of Allergy and Infectious

                                    Diseases

1987-89                       AIDS Investigator Award K87SF057, California State

                                    Task Force on AIDS

1989-92                       Children's Hospital of San Francisco Grant 89-023

1990-93                       Children's Hospital of San Francisco Grant 90-041

1991-93                       California Pacific Medical Center Grant 91-030

1989-94                       Elizabeth Reed Taylor Foundation Grant

1994-96                       DATA Research Grant

1999-2003                   American Medical Association Physician’s Recognition Award

2001                            San Francisco Magazine “500 Best Doctors” Award

  

Organizations and Licenses

 

1979                            Diplomate, National Board of Medical Examiners

1981                            Diplomate, American Board of Internal Medicine

1978-81                       New York State Medical License #138648

1981-Present               California State Medical License #G44866

1978-Present               Member, Southern Medical Association

1983-88                       Associate, American Medical Association

1987-Present               Member, American Association for the Advancement of Science

1987-Present               Member, American Federation for Clinical Research

1988-Present               Member, American Society of Hematology

1990-Present               Member, American Society For Apheresis (ASFA)

1990-Present               Member, Community Consortium of San Francisco

1990-Present               Member, International AIDS Society

1991-Present               Member, Clinical Immunology Society

1992-Present               Member, New York Academy of Sciences

1995-Present               Member, San Francisco Medical Society

1995-Present               Member, California Medical Association

1995-Present               Member, European Haematology Association

1995-Present               Member, California Blood Bank Society

1997-Present               Member, International Council on Infertility Information Dissemination (INCIID)

2000                            Diplomate, National Baromedical Services Training Program, Columbia, SC

2000-Present               Board Member, Lyme Disease Resource Center, Ukiah, CA

2000-Present               Board Member, International Lyme and Associated Diseases Society (ILADS)

 

 

Professional and Teaching Experience

 

1974-75                       Anatomy Dissection Instructor, University of Lausanne Medical School

1978-81                       Visiting Clinical Fellow, Columbia University College of Physicians and Surgeons

1982-89                       Hematology Course Instructor, Introduction to Clinical Medicine, UCSF School of Medicine

1985-88                       Attending Physician, Cancer Research Institute, UCSF

1985-89                       Attending Physician, Hematology Service, San Francisco General Hospital

1985-89                       Attending Physician, Laboratory Medicine Hematology Service, UCSF

1989-91                       Attending Physician, Hematology/Internal Medicine, Children's Hospital of San Francisco

1990-91                       Advisor, California Blue Shield Medical Policy Committee on Quality and Technology

1990-91                       Editor-at-Large, Marcel Dekker Medical Publications

1991-Present               Attending Physician, Hematology/Internal Medicine, California Pacific Medical Center, San Francisco

1992-96                       Medical Advisor, Grupo de Apoio a Prevencao a AIDS (GAPA), Brazil

1993-Present               Medical Director, International DNCB Study Group, San Francisco

1995-96                       Scientific Advisory Committee, Co-factors Study Group, Paris, France

1996-Present               Attending Physician, St. Francis Memorial Hospital, San Francisco

1996-Present               Attending Physician, Chinese Hospital, San Francisco

1999-Present               Attending Physician, St. Mary’s Medical Center, San Francisco

1999-Present               Attending Physician, Seton Medical Center, Daly City, CA

1999                            Program Project Reviewer, National Institute of Diabetes, Digestive & Kidney Diseases, Bethesda, MD

2000-2001                   Attending Physician, Hyperbaric Medicine Service, St. Francis Hospital, San Francisco

2000-Present               Member, California Lyme Disease Advisory Committee

 

 

 

Research Experience

 

1970-71                       Senior College Research Project:  Pica in Rats.  Department of Physiological Psychology, Columbia College, Dr. S. Woods.

 

1971-72                       Clinical Research in Endocrinology. Columbia-Presbyterian Medical Center, New York, NY, Dr. R. Vande Wiele.

 

1974-75                       Neurobiological Research on Rat Sensory Receptors.  University of Lausanne Medical School, Dr. H. Van der Loos.

 

1979-80                       Clinical Research on Circulating Immune Complexes.  St. Lukes-Roosevelt Hospital Center, Dr. W. Clark.

 

1982-85                       NIH Grants # HL-07100-08 454965-31779 and 1F32 HL-06871-01 CLN:  Study of Autoantibody in Immune Thrombocytopenic Purpura by a Monoclonal Technique.  Cancer Research Institute, University of California San Francisco, Dr. M.Shuman.

 

1985-87                       Research Fellowships 85-N27 and 86-37A.  American Heart Association, California Affiliate:  Characterization of Platelet Antibodies. Cancer Research Institute and Department of Laboratory Medicine, University of California San Francisco, Drs. M. Shuman & L. Corash.

 

1986-87                       AIDS Clinical Research Center Grant:  Chloroquine Treatment of AIDS-Related Immune Thrombocytopenic Purpura (ITP), Drs. D. Abrams & L. Corash

 

1987-89                       NIH RO1 #AI/HL 24288, National Heart, Lung and Blood Institute/National Institute of Allergy and Infectious Diseases:  Pathogenesis of AIDS-Related Immune Thrombocytopenic Purpura.

 

1987-89                       AIDS Investigator Award K87SF057, California State Task Force on AIDS:  Autoimmunity and AIDS.

 

1987-89                       Research Award R87SFO89, California State Task Force on AIDS:  Autoimmunity and AIDS.

 

1988-89                       AIDS Clinical Research Center Grant:  Monthly Intravenous Gammaglobulin Treatment of AIDS-Related Immune Thrombocytopenia.  Drs. D. Abrams, M. Jacobson & T. Chew.

 

1989-92                       Children's Hospital of San Francisco Grant 89-023: Pathogenesis of HIV-Associated Peripheral Neuropathy.  Drs. D. Kiprov, D. Bredesen.

 

1990-93                       Children's Hospital of San Francisco Grant 90-041: The Clinical Significance of LEU 17 T-Cells in HIV Disease.  Drs. D. Kiprov, J. Giorgi.

 

1991-93                       California Pacific Medical Center Grant 91-030: Comparison of Intravenous Gammaglobulin vs. Allogeneic Lymphocyte Immunization in Women with Recurrent Spontaneous Abortions - A Double Blind Crossover Study.  Drs. D. Kiprov, R. Nachtigall, C. Levinson.

 

1989-94                       Elizabeth Reed Taylor Foundation Grant: Peripheral Blood Lymphocyte Subset and Epidermal Langerhans Cell Evaluation in AIDS/ARC during DNCB Application.  Drs. W. Epstein, T. Berger.

 

1993-95                       Co-investigator, Passive Hyperimmune Therapy Program.  Dr. J. Levy, HemaCare Corporation.

 

1993-96                       Consultant, Swedish DNCB Study Group.  Drs. S. Britton, L. Morfeldt, K. Liebman.

 

1994-96                       Co-investigator, DNCB Topical Delivery System Development Project.  Drs. W. Epstein, L.B. Mills, Y.S. Zhu.

 

1994-96                       DATA Research Grant:  Quantitation of Viral Load in HIV-Infected Patients Treated with DNCB.  Drs. Y.S. Zhu, W. Epstein, L.B. Mills.

 

1996-99                       IND Co-investigator:  Evaluation of Topical Dinitrochlorobenzene Therapy in Humans.  Queens Medical Center, Honolulu, HI.  Drs. L.B. Mills, R.I. Frankel, W.L. Epstein.

 

 

Professional Activity:

 

Invited Lectures

 

International

 

Research Seminar, Pasteur Institute, Paris, France

Research Seminar, Karolinska Institute, Stockholm, Sweden

Plenary Session, IV International Conference on HIV/AIDS in Cuba, Central America and the Carribbean, Havana, Cuba

 

National

 

Hematology Rounds, Albert Einstein Medical Center, New York, NY

Research Seminar, American Red Cross Headquarters, Washington, DC

Hematology/Coagulation Rounds, Mt. Sinai Medical Center, New York, NY

Hematology Rounds, Memorial-Sloan Kettering Cancer Center, New York, NY

Hematology Grand Rounds, University of California, Los Angeles, CA

HemaCare Stem Cell Symposium, Los Angeles, CA

AIDS Seminar, National Institute of Allergy & Infectious Diseases, Bethesda, MD

DNCB Symposium, Broward Educational AIDS Conference on Health (BEACH ‘94), Ft. Lauderdale, FL

Allied Health Seminar, ASFA National Meeting, San Diego, CA

ILADS Clinical Conference, Princeton, NJ

ILADS Annual Meeting, Basking Ridge, NJ

 

 

 

Regional

 

 

Invited Reviewer

 

 

Scientific and Professional Meetings:

 

International

 

1986                            International Conference on AIDS, Paris, France (Poster)

1988                            International Conference on AIDS, Stockholm, Sweeden (Poster)

1988                            International Conference on Retroviruses and Disease, Heraklion, Crete (Poster)

1989                            International Conference on AIDS, Montreal, Canada (Paper)

1989                            International Conference on Neurological Complications of HIV           

                                    Infection, Quebec City, Canada (Paper)

1990                            International Conference on Management Issues in HIV Disease, Munich, Germany (Paper)

1990                            International  Conference  on the  Uses of  Intravenous Gammaglobulin, Interlaken, Switzerland (Paper)

1990                            International Conference on AIDS, San Francisco, CA (Poster)

1991                            International Conference on AIDS, Florence, Italy (Posters)

1992                            International Conference on AIDS, Amsterdam, Holland

                                    (Poster)

1993                            International Conference on AIDS, Berlin, Germany (Poster)

1994                            International Conference on AIDS, Yokohama, Japan (Poster)

1995                            International Symposium on Clinical Immunology, San Francisco,

                                    CA (Paper)

1995                            Third International Conference on AIDS in Asia and the Pacific,

                                    Chiang Mai, Thailand (Paper)

1996                            International Conference on AIDS, Vancouver, Canada (Poster)

1997                            International Symposium on Clinical Immunology, Amsterdam, Holland (Poster)

1997                            International Society of Hematology Meeting, Stockholm, Sweden (Poster)

1998                            12th World AIDS Conference, Geneva, Switzerland (Symposium)

1998                            International Conference on the Discovery and Clinical Development of Antiretroviral Therapies (ICDCD), St. Thomas, V.I. (Poster)

1999                            International Conference on HIV, Leukemia and Cancer, Marrakech, Morocco (Poster)

1999                            International Society of Hematology Meeting, Barcelona, Spain (Poster)

2000                            Second International Conference on Experimental and Clinical Reproductive Immunobiology, Amsterdam, Holland (Poster)

 

National

 

1981-2001                   American Society of Hematology Annual Meeting (Papers, Posters)

1983-95                       American Federation for Clinical Research Annual Meeting (Papers)

1990-96                       American Society for Apheresis Annual Meeting (Papers)

1997-2000                   AAAI/AAI/CIS Joint Meeting (Posters)

2001                            First Annual FOCIS Meeting, Boston, MA (Poster)

2001                            American Society for Reproductive Immunology Meeting (Poster)

2002                            Second Annual FOCIS Meeting, San Francisco, CA (Poster)

 

Regional                      

 

1985, 1988                  University of California Task Force on AIDS Research Symposium,

                                    San Diego, CA (Papers)

1987                            California Heart Association Young Investigator Symposium, Santa

                                    Barbara, CA (Paper)

 

 

University Service:

 

School of Medicine, UCSF

 

1982-89                       Introduction to Clinical Medicine - Advisory Panel 

1988                            Qualifying Examination Reviewer, Department of Anatomy

1988-89                       Course Co-director, Laboratory Medicine 150:01 (Medical Student Elective)

 

Department of Laboratory Medicine, UCSF

 

1986-89                       Ad Hoc Faculty Committee on Merits and Promotions

 

Department of Medicine, UCSF

 

1987-89                       Ad Hoc Faculty Committee on Merits and Promotions

 

Cancer Research Institute, UCSF

 

1987-88                       Library Committee

 

Medical Society Service:

 

1993-94                       Membership Committee, ASFA

1994-96                       Co-Chairman, Membership Committee, ASFA

1995-96                       Member, CBBS Apheresis Committee

1998                            Member, CBBS Scientific Advisory Committee

 

Medicolegal Consulting


Publications

 

            1.         Stricker RB, Linker CA.  Pernicious anemia, 18q deletion syndrome, and IgA deficiency.  JAMA 1982;248:1359-1360.

 

            2.         Volberding P, Conant MA, Stricker RB, Lewis BJ.  Chemotherapy in advanced Kaposi's sarcoma:  Implications for current cases in homosexual men.  Am J Med 1983;74:652-656.

 

            3.         Stricker RB, Linker CA.  Acute lymphoblastic leukemia with monosomy 7 in a Hiroshima survivor 37 years after the bomb.  JAMA 1983;250:640-641.

 

            4.         Kay J, Stricker RB.  Hematologic and immunologic abnormalities in anorexia nervosa.  South Med J 1983;76:1008-1011.

 

            5.         Stricker RB, Shuman MA.  Aplastic anemia complicating systemic lupus erythematosus:  Response to androgens in two patients.  Am J Hematol 1984;17:193-201.

 

            6.         Peterson SP, Schiller N, Stricker RB.  Failure of two-dimensional echocardiography to detect Aspergillus endocarditis.  Chest 1984;85:291-294.

 

            7.         Stricker RB, Wong D, Saks SR, Corash L, Shuman MA.  Acquired Bernard-Soulier syndrome.  J Clin Invest 1985;76:1274-1278.

 

            8.         Stricker RB, Abrams DI, Corash L, Shuman MA.  Target platelet antigen in homosexual men with immune thrombocytopenia.  N Engl J Med 1985;313:1375-1380.

 

            9.         Stricker RB, Linker CA, Crowley TJ, Embury SH.  Hematologic malignancy in sickle cell disease:  Report of four cases and review of the literature.  Am J Hematol 1986;21:223-230.

 

            10.       Stricker, RB, Shuman MA.  Quinidine purpura:  Evidence that glycoprotein V is a target platelet antigen.  Blood 1986;67:1377-1381

 

            11.       Stricker, RB, Wong D, Shiu D, Reyes PT, Shuman MA.  Activation of plasminogen by tissue plasminogen activator on normal and thrombasthenic platelets:  Effects on surface proteins and platelet aggregation.  Blood 1986;40:515-524.

 

            12.       Morrow WJW, Wharton MM, Stricker RB, Levy JA.  Analysis of immune complexes in the sera of patients with AIDS.  Clin Immunol Immunopathol 1986;40:515-524.

 

            13.       Stricker RB, Reyes PT. Corash L, Shuman MA.  Evidence that a 210,000-dalton protein (GP 210) serves as a platelet F(c) receptor.  J Clin Invest 1987;79:1589-1594.

 

            14.       Stricker RB, Lewis BH, Corash L, Shuman MA.  Post-transfusion purpura associated with a platelet autoantibody.  Blood 1987;69:1458-1463.

 

            15.       Stricker RB, McHugh TM, Moody DJ, Morrow WJW, Stites DP, Shuman MA, Levy JA.  An AIDS-related autoantibody reacts with a specific antigen on stimulated CD4+T-cells.  Nature 1987;327:710-713.

 

            16.       Valone FH, Stricker RB, Zamora PO, Shah VO, Mann PL.  Technitium-99m labeled 50 H.19 antibody fragments:  Interaction of the antibody with platelets.  Nuclear Medicine Biol 1988;15:439-450.

 

            17.       Stricker RB, Lane PK, Leffert JD, Rodgers GM, Shuman MA, Corash L.  Development of anti-thrombin antibodies following surgery in patients with prosthetic cardiac valves.  Blood 1988;72:1375-1380.

 

            18.       McHugh TM, Stites DP, Busch MP, Krowka JF, Stricker, RB, Hollander H.  Relationship of circulating levels of HIV antigen, anti-P24 antibody and HIV-containing immune complexes in patients infected with HIV.  J Infect Dis 1988;158:1088-1091.

 

            19.       Fultz PN, Stricker RB, McClure HM, Anderson DC, Switzer WM, Horaist C.  Humoral response to SIV/SMM infection in macaque and mangabey monkeys.  J Acquired Immun Defic Syndrome 1990;3:319-329.

 

            20.       Fultz PN, Siegel RS, Brodie A, Mawie AC, Stricker RB, Swenson RB, Anderson DC, McClure HM.  Prolonged CD4+ lymphocytopenia and thrombocytopenia in a chimpanzee persistently infected with HIV-1.  J Infect Dis 1991;163:441-447.

           

            21.       Morrow WJW, Isenberg DA, Sobol RE, Stricker RB, Kieber-Emmons T.  AIDS virus infection and autoimmunity.  Clin Immunol Immunopathol 1991;58:163-180.

           

            22.       Stricker, RB, Elswood BF, Abrams DI.  Dendritic cells and dinitrochlorobenzene (DNCB):  A new treatment approach to AIDS.  Immunol Letters 1991;29:191-196.

 

            23.       Stricker RB, Main EK, Kronfield J, Kallas GS, Gerson LB, Autry AM, Kiprov DD. Severe post-partum eclampsia: Response to plasma exchange.  J Clin Apheresis 1992;7:1-3.

 

            24.       Lalwani RB, Stricker, RB.  Successful use of antifibrinolytic therapy in acquired factor VIII deficiency.  Am J Med Sci 1992;303:398-401.

 

            25.       Stroncek DF, Kline WE, Clay ME, Plachta L, Stricker RB, Hollander H, Greenspan J, Skubitz K.  Antibodies to granulocytes in patients infected with HIV.  J Lab Clin Med 1992;119:724-731.

           

            26.       Stricker RB, Davis JA, Gershow J, Yamamoto K, Kiprov DD.  Thrombotic thrombocytopenic purpura complicating systemic lupus erythematosus:  Report of a case and review of the literature from the plasmapheresis era.  J Rheumatol 1992;19:1469-1473.

 

            27.       Stricker RB, Sanders KA, Owen WF, Kiprov DD, Miller RG.  Mononeuritis multiplex associated with cryoglobulinemia in HIV infection.  Neurology 1992;42:2103-2105.

 

            28.       Stricker RB, Miller RG, Kiprov DD.  Role of plasmapheresis in acute disseminated (postinfectious) encephalomyelitis.  J Clin Apheresis 1992;7:173-179.

 

            29.       Stricker RB, Zhu YS, Elwood BF, Dumlao C, Van Elk J, Berger TG, Tappero J, Epstein WL, Kiprov DD.  Pilot study of topical dinitrochlorobenzene (DNCB) in human immunodeficiency virus infection.  Immunol Letters 1993;36:1-6.

 

            30.       Stricker RB, Kwiatkowska BJ, Habis JA, Kiprov DD.  Myasthenic crisis: Response to plasmapheresis following failure of intravenous gammaglobulin.  Arch Neurol 1993;50:837-840.

 

            31.       Elswood BF, Stricker RB.  Polio vaccines and the origin of AIDS. Medical Hypotheses 1994;42:347-354.

 

            32.       Stricker RB, Barlogie B, Kiprov DD. Acquired factor VIII inhibitor associated with chronic alpha-interferon therapy.  J Rheumatol 1994;21:350-352.

           

            33.       Andrews BT, Stricker RB, Kitt D, Galanakis DK, Gerson LB, Hieshima G.  Treatment of an intracranial arteriovenous malformation in a patient with complicated hemophilia:  Report of a case.  Am J Med Sci 1994;308:106-109.

 

            34.       Stricker RB, Elswood BF, Goldberg B, Dumlao C, Van Elk J, Henry J, Winger EE, Epstein WL.  Clinical and immunologic evaluation of HIV-infected patients treated with dinitrochlorobenzene (DNCB).  J Am Acad Dermatol 1994;31:462-466.

 

            35.       Stricker RB, Zhu YS, Elswood BF.  Quantitation of human immunodeficiency virus type 1 (HIV-1) RNA in plasma: Clinical correlates.  Res Virol 1995;146:151-158.

 

            36.       Stricker RB, Goldberg B, Mills LB, Epstein WL.  Improved results of delayed-type hypersensitivity skin testing in HIV-infected patients treated with topical dinitrochlorobenzene (DNCB).  J Am Acad Dermatol 1995;33:608-611.

 

            37.       Stricker RB, Goldberg B.  Increase in lymphocyte subsets following treatment of HIV-associated neutropenia with granulocyte colony-stimulating factor.  Clin Immunol Immunopathol 1996;79:194-196.

 

            38.       Goldberg B, Stricker RB.  HIV protease and the pathogenesis of AIDS. 

                        Res Virol 1996;147:375-379.</