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Immunodeficiency/AIDS Clinic |
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Immunodeficiency/AIDS Clinic |
| Side Effects of DNCB |
When protocols are followed, DNCB results in no serious side effects. DNCB, like coffee, tea and celery, causes chromosome mutations in bacteria 18. However, studies in laboratory animals and humans have conclusively shown that DNCB is not a carcinogen 19. In fact, during the 70 years that DNCB has been used for medical purposes in humans, there is no evidence that cancers have developed as a result of applying DNCB to the skin. In AIDS patients, excessive applications of DNCB have resulted in toxic skin reactions 20. For some time, however, the DNCB dosage has been standardized using the Epstein protocol 10. When this protocol is used, excessive skin reactions have been effectively controlled with local measures such as calomine lotion and cold camomile compresses 10 , 14. No infections have been seen as a result of these reactions. Other indications of the tolerance of humans to treatment with DNCB can be found in the descriptions of pilot studies and controlled clinical trials of DNCB therapy on the page listed below. 8 , 10 , 14. |
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